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近年来,随着免疫学理论和技术的进展,利用免疫学方法研究矽肺发病机理取得某些成果,通过实验观察可以说明矽肺发病过程中有免疫因素参与。且从免疫学角度能够合理地解释矽肺发病中某些病理现象。如:为什么矽肺病人脱离接尘后疾病仍继续发展;为什么矽肺病人群中有个体差异性;为什么矽肺合并结核二者互为因果,使病情更加恶化急转直下等等,但是迄今为止,对矽肺发病免疫学本质及其内在联系仍未阐明,还有很多问题尚待深入研究。本文试图联系自身免疫性线索对矽肺发病机理进行讨论。
In recent years, with the progress of immunology theory and technology, the use of immunological methods to study the pathogenesis of silicosis to achieve some results through experimental observations may explain the immune factors involved in the pathogenesis of silicosis. And from the immunological point of view can reasonably explain some of the pathological signs of silicosis. Such as: why silicosis patients continue to develop after the disease from the dust; why there are individual differences in the population of silicosis; why silicosis and tuberculosis both cause and effect each other, the disease worsened so far, but so far, the immune response to silicosis The essence of science and its internal relations have not yet been clarified. There are still many problems to be studied in depth. This article attempts to address the pathogenesis of silicosis in connection with autoimmune clues.