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凋亡抑制因子Survivin是凋亡抑制蛋白(IAP)家族的最新成员〔1〕,是Altieri等(1997)利用效应细胞蛋白酶受体-1(effector cell protease re-ceptor 1,EPR1)cDNA在人类基因组库中筛选分离出的一个哺乳动物凋亡抑制因子,已被测定并绘出完整的基因图谱,其组织分布具有明显的细胞选择
Survivin is a new member of the apoptosis-inhibitory protein (IAP) family [1]. It is a result of Altieri et al. (1997) using the cDNA of effector cell protease re-ceptor 1 (EPR1) in the human genome A mammalian inhibitor of apoptosis isolated from a library has been sequenced and a complete genetic map has been drawn with a clear cell selection of tissue distribution