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目的探讨急性桥脑梗死患者不同治疗方法对预后的影响。方法对2008年10月～2010年10月期间某科连续收治的急性桥脑梗死患者进行回顾性分析,根据治疗方法不同分为肝素抗凝治疗组和抗血小板治疗组,记录患者入院时NIHSS评分、mRS评分、BI评分,记录患者既往病史、脑梗死危险因素,患者头颅CT和MRI结果,对所有患者于治疗后6个月时进行随诊并评分,所得结果进行统计学分析。结果两组患者年龄、性别、既往史、引起脑梗死的危险因素等基本情况方面差异无统计学意义,具有可比性。治疗前抗凝组NIHSS评分、mRS评分、BI评分分别为(3.36±3.26)、(1.82±1.04)和(75.45±25.99)分,抗血小板组分别为(2.71±3.09)、(1.67±1.02)和(81.28±24.90)分,两组比较差异无统计学意义;治疗后6个月两组患者NIHSS评分、mRS评分、BI指数分别为(1.64±2.32)、(1.15±0.83)分、(87.58±16.59)和(1.69±2.81)、(0.94±0.79)分、(89.6±18.20),与治疗前相比,两组患者治疗前后得分差异有统计学意义,对两种治疗方法 6个月后的得分进行比较,差异无统计学意义。结论抗凝治疗与抗血小板治疗对急性桥脑梗死疗效可靠。
Objective To investigate the influence of different treatment methods on prognosis in patients with acute cerebral infarction. Methods A retrospective analysis was performed on patients with acute cerebral infarction who were admitted to our hospital from October 2008 to October 2010. The patients were divided into heparin anticoagulation therapy group and antiplatelet therapy group according to different treatment methods. The NIHSS score , MRS score and BI score. The patients’ past medical history, risk factors of cerebral infarction, head CT and MRI were recorded. All the patients were followed up and scored 6 months after treatment. The results were statistically analyzed. Results There was no significant difference between the two groups in basic conditions such as age, sex, past history and risk factors of cerebral infarction, which were comparable. NIHSS score, mRS score and BI score were (3.36 ± 3.26), (1.82 ± 1.04) and (75.45 ± 25.99) in the anticoagulant group before treatment, respectively, while those in the antiplatelet group were (2.71 ± 3.09) and (1.67 ± 1.02) And (81.28 ± 24.90) points respectively. There was no significant difference between the two groups (NIHSS score, mRS score and BI index were (1.64 ± 2.32), (1.15 ± 0.83), (87.58 ± 16.59) and (1.69 ± 2.81), (0.94 ± 0.79) and (89.6 ± 18.20), respectively. Before and after treatment, there was significant difference between the two groups before and after treatment. After 6 months Scores were compared, the difference was not statistically significant. Conclusion Anticoagulant therapy and antiplatelet therapy are effective in treating acute cerebral infarction.