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绿脓杆菌性角膜溃疡是一种最严重的化脓性角膜炎，若未及时有效地治疗，预后差，临床上一般首选多粘菌素Ｂ治疗。本文报道了应用妥布霉素治疗绿脓杆菌性角膜溃疡１５例，其中４５岁以下的占９０％。角膜溃疡的诱因中戴用接触镜引起占３３％。除２例就诊太晚外，其余患者均得到治愈，视力恢复较满意。笔者强调了在做好预防戴用接触镜引起角膜感染工作的同时，要及时有效地治疗。对妥布霉素和多粘菌素Ｂ在治疗绿脓杆菌性角膜溃疡方面的优点缺点进行了讨论。
Pseudomonas aeruginosa corneal ulcer is one of the most serious suppurative keratitis, if not effectively treated in time, the prognosis is poor, the clinical choice of polymyxin B treatment. This article reports the application of tobramycin treatment of Pseudomonas aeruginosa corneal ulcer in 15 cases, of which 45 years of age accounted for 90%. The cause of corneal ulcer wearing contact lenses accounted for 33%. Except two cases of treatment too late, the rest of the patients were cured, satisfactory recovery of visual acuity. The author emphasizes the prevention of wear contact lenses cause corneal infection at the same time, to be timely and effective treatment. The advantages and drawbacks of tobramycin and polymyxin B in the treatment of Pseudomonas aeruginosa ulcer were discussed.