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目的:了解某三级甲等医院心脏起搏器植入术围术期预防用抗菌药物情况。方法:采用回顾性调查方法,对该院2009-2011年372例行心脏起搏器植入术的患者病历资料进行调查分析。结果:心脏起搏器植入术患者围术期预防用抗菌药物应用率为80.1%,共涉及6大类20个品种,多为单一用药,以注射用五水头孢唑林钠应用率最高(达32.4%),给药途径均为静脉滴注。结论:该院心脏起搏器植入术围术期预防用抗菌药物不合理情况构成比呈逐年下降趋势。近年在该院一系列促进抗菌药物规范化使用的干预措施下,抗菌药物预防应用逐步规范,但离卫生部的要求还有一定差距。今后还需采取更为有效的干预措施,规范临床医师用药行为,提高围术期预防用抗菌药物的合理性。
Objective: To understand the perioperative prophylactic use of antimicrobial agents in a pacemaker implanted in a tertiary hospital. Methods: A retrospective survey was conducted to investigate the medical records of 372 patients undergoing cardiac pacemaker implantation from 2009 to 2011 in this hospital. Results: The rate of perioperative prophylaxis with antibacterials was 80.1% in patients undergoing cardiac pacemaker implantation, involving a total of 20 varieties in 6 major categories, mostly single drug, with the highest rate of application of cefazolin sodium pentahydrate for injection Up to 32.4%), the route of administration is intravenous drip. CONCLUSION: The irrational use of antimicrobial agents for perioperative prophylaxis of cardiac pacemaker implants has been declining year by year. In recent years, the hospital a series of anti-bacterial drugs to promote the standardization of the use of interventions, the gradual normative application of antimicrobial prophylaxis, but there is a certain gap between the requirements of the Ministry of Health. In the future, we must take more effective interventions to regulate the use of clinicians and enhance the rational use of antimicrobial agents for perioperative prevention.