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目的:探讨脑出血患者的细胞免疫功能及临床意义。方法 :对46例脑出血患者及42例正常者外周血T淋巴细胞亚群及血清可溶性白细胞介素 -2受体(slL -2R)水平进行检测 ,并对其中21例脑出血患者恢复期进行复查。结果 :脑出血急性期及病情重、预后差者外周血CD3数量、CD4/CD8比值明显降低 ,而CD8、slL -2R显著升高 ,而恢复期结果与之相反。结论 :脑出血患者细胞免疫功能明显低下 ,检测外周血T淋巴细胞亚群分布及血清slL -2R水平对判断脑出血病情、预后有一定的临床意义。
Objective: To investigate the cellular immune function in patients with intracerebral hemorrhage and its clinical significance. Methods: The levels of T lymphocyte subsets and serum soluble interleukin-2 receptor (IL-2R) in peripheral blood of 46 patients with cerebral hemorrhage and 42 normal controls were detected, and 21 patients with ICH were recruited Review. Results: The number of CD3 and the ratio of CD4 / CD8 in acute cerebral hemorrhage and serious illness and poor prognosis were significantly decreased, while the levels of CD8 and slL -2R were significantly increased, while the convalescence results were the opposite. Conclusion: The cellular immune function of patients with intracerebral hemorrhage is obviously low. The distribution of T lymphocyte subsets and the level of serum slL -2R in peripheral blood are of clinical significance in judging the prognosis of cerebral hemorrhage.