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本文检测了铅接触、铅吸收和铅中毒者的体液免疫功能和Ｔ淋巴细胞亚群的变化，结果发现各组ＩｇＧ、ＩｇＭ、ＯＫＴ＿３、ＯＫＴ＿４、Ｔ＿４／Ｔ＿８均明显低于对照组，铅中毒组最为显著，且ＯＫＴ＿８亚群相对增高。并对其进行动态观察，探讨它在铅中毒诊断和恢复监护中的价值。本研究表明，铅对机体体液和细胞免疫功能具有明显的抑制作用，Ｔ细胞亚群中以具有诱导和辅助功能的细胞亚群受抑制最明显，ＯＫＴ＿４、Ｔ＿４／Ｔ＿８等可作为铅中毒的早期诊断和康复监护的敏感指标之一。
The results showed that IgG, IgM, OKT_3, OKT_4 and T_4 / T_8 in all groups were significantly lower than those in control group and lead poisoning group The most significant, and OKT_8 subpopulation relative increase. And observe it dynamically to explore its value in the diagnosis and recovery of lead poisoning. This study showed that lead had significant inhibitory effects on body fluid and cellular immune function. The inhibition of the cell subpopulation with induction and auxiliary functions in T cell subsets was the most obvious. OKT_4 and T_4 / T_8 could be the early lead poisoning One of the sensitive indicators of diagnosis and rehabilitation monitoring.