论文部分内容阅读
巨噬细胞集落刺激因子(macrophage colony-stimu-lating factor,M-CSF)是一种多功能细胞因子,具有促进单核—巨噬细胞生长、增殖、分化等功能。M-CSF以可溶型和膜结合型等多种形式存在,在髓细胞白血病、卵巢癌、乳腺癌等肿瘤细胞中高表达。M-CSF受体(M-CSFR)是原癌基因C-fms编码的跨膜蛋白。近年
Macrophage colony-stimu-lating factor (M-CSF) is a multifunctional cytokine that promotes the growth, proliferation and differentiation of monocytes and macrophages. M-CSF is soluble and membrane-bound and other forms exist, in myeloid leukemia, ovarian cancer, breast cancer and other tumor cells in high expression. The M-CSF receptor (M-CSFR) is a transmembrane protein encoded by the proto-oncogene C-fms. in recent years