A Facile Synthesis of N-Phosphoryl Amino Acids Containing Hydroxy Group

• 出 处: Chinese Chemical Letters
• 发表日期: 2004年06期
• 关键词: ammonium bromide hydroxyl adding substituted ambient hydroxide dissolved remarka

three kinds of N-(diisopropyloxyphosphoryl) amino acids containing hydroxyl group were prepared in high yield by using diisopropyl phosphite as the phosphorylating agent, sodium hypochlorite as the chlorinating agent and tetrabutyl ammonium bromide as the phase transfer catalyst in basic aqueous media.

three kinds of N- (diisopropyloxyphosphoryl) amino acids containing hydroxyl group were prepared in high yield by using diisopropyl phosphite as the phosphorylating agent, sodium hypochlorite as the chlorinating agent and tetrabutyl ammonium bromide as the phase transfer catalyst in basic aqueous media.