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目的:研究海洛因滥用者梅毒螺旋体的感染情况,了解这一人群梅毒螺旋体感染的上升势头,探索减少梅毒螺旋体传播的途径。方法:采用梅毒甲苯胺红不加热血清试验(TRUST)对4178例海洛因滥用者进行初筛,阳性者用梅毒螺旋体明胶颗粒凝集试验(TPPA)进行确诊。结果:4178例海洛因滥用者中梅毒螺旋体感染者128例,占3.06%,其中男性50例,女性78例;感染者以静脉、肌肉注射为主,共有106例占83%。静脉注射者最短者一个月,最长164个月。女性滥用者中梅毒感染率为6.9%,明显高于男性滥用者中梅毒感染率1.64%,这说明女性更易感染梅毒。结论:海洛因滥用者是梅毒螺旋体易感人群;静脉注射毒品是感染梅毒的主要途径之一,另外相当一部分女性吸毒者卖淫等性病感染高危行为,造成了梅毒感染率的加大,因此加强毒品的滥用和梅毒的预防工作有利于截止梅毒的流行和传播。
Objective: To study the infection of Treponema pallidum in heroin abusers, understand the rising tendency of Treponema pallidum infection in this population, and explore ways to reduce the transmission of Treponema pallidum. Methods: A total of 4178 cases of heroin abusers were screened by TRUST (TRUST). The positive patients were diagnosed by TPPA (Treponema pallidum Gelatin Particle Agglutination Test). Results: Among 4178 cases of heroin abusers, there were 128 cases of Treponema pallidum infection, accounting for 3.06%, including 50 males and 78 females. Infected persons were mainly intravenous and intramuscular injection, with 106 cases accounting for 83%. Intravenous injection of the shortest one month, up to 164 months. The prevalence of syphilis among female abusers was 6.9%, significantly higher than that of male abusers (1.64%), indicating that women are more likely to be infected with syphilis. Conclusion: Heroin abusers are susceptible to Treponema pallidum. Intravenous injection of drugs is one of the main ways of syphilis infection. In addition, a considerable number of female drug users engage in high risk behaviors such as prostitution and sexually transmitted infections, resulting in an increase in the rate of syphilis infection. Therefore, Prevention of syphilis abuse and syphilis is conducive to the epidemic of syphilis and spread.