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目的考察某院抗菌药物的使用现状,推进临床合理应用抗菌药物再上新台阶。方法采用观察和回顾性调查方法,根据世界卫生组织(WHO)推荐的抗菌药物合理使用国际指标(16项)及医疗机构抗菌药物临床应用月统计表国内指标(4项),对某院住院患者抗菌药物使用情况进行调研分析。结果通过干预,2014~2016年住院患者使用抗菌药物的总例数与消耗量较出院人数的增长较缓(P<0.5),抗菌药物费用占医院总费用的百分率均不高于10%,20项指标中,4项宏观指标较好,2项已达标,12项有不同程度的改善。结论某院抗菌药物的使用基本合理,医院需持续对其使用率、使用强度、手术切口预防用药、静脉输液占比等指标强化干预,鼓励药师多种模式下临床指导用药是必要的。
Objective To investigate the status quo of the use of antibiotics in a hospital and promote the rational use of antibiotics in clinical trials to a new level. Methods According to the international recommended indicators of rational use of antimicrobial agents (16 items) recommended by the World Health Organization (WHO) and the national indicators (4 items) of monthly statistics of clinical application of antimicrobial agents by medical institutions, the methods of observation and retrospective investigation were used to evaluate the inpatient Antimicrobial use of research and analysis. Results Interventions showed that the total number of patients using antimicrobials and the consumption of narcotic drugs increased more slowly than those discharged from hospitals in 2014-2016 (P <0.5), and the percentage of antibacterial drugs in total hospital costs was no higher than 10%. 20 Among the indicators, 4 are good macroeconomic indicators, 2 have achieved compliance and 12 have some degree of improvement. Conclusion The use of antibacterials in a hospital is basically reasonable. The hospital should continue to intensify interventions such as its usage rate, intensity of use, prophylactic use of surgical incision, and proportion of intravenous infusion. It is necessary to encourage pharmacists to guide clinical use in various modes.