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目的分析肾移植后严重并发症时免疫抑制剂药物的调整效果。方法选取医院收治的50例接受肾移植术后产生肺部感染、出血以及尿漏等严重并发症的患者作为研究对象,对其临床资料进行回顾性分析。50例患者中18例症状相对较轻患者接受常规免疫抑制剂使用量减半的治疗方式;32例重症并发症患者全部停用相应免疫抑制剂,并且静脉滴注适量甲泼尼龙以及进行抗感染等治疗,待并发症得到控制后逐渐恢复免疫抑制剂常规应用。结果症状较轻的18例患者均治愈出院,痊愈率为100.00%;32例重症患者中治愈出院26例,死亡6例,痊愈率为81.25%。结论肾移植术后产生严重并发症时,适当减少或者短时间停用免疫抑制药物是相对安全有效的,具有积极的临床应用价值。
Objective To analyze the effect of immunosuppressive agents in the treatment of serious complications after kidney transplantation. Methods A total of 50 hospitalized patients who underwent severe renal complications such as pulmonary infection, hemorrhage, and urinary leakage after renal transplantation were selected as the study subjects, and their clinical data were retrospectively analyzed. Among the 50 patients, 18 patients with relatively mild symptoms received half the dose of conventional immunosuppressants. All 32 patients with severe complications were discontinued with appropriate immunosuppressive agents, and intravenous drip of methylprednisolone and anti-infective And other treatment, to be controlled after the gradual restoration of immunosuppressive agents routine application. Results 18 patients with mild symptoms were cured and discharged. The cure rate was 100.00%. Among 32 severe cases, 26 patients were cured and discharged, and 6 patients died. The cure rate was 81.25%. Conclusion When severe complications occur after renal transplantation, it is relatively safe and effective to reduce or shorten the immunosuppressive drugs for a short period of time, which has positive clinical value.