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对７例早期胃癌和４２例中晚期胃癌活检组织，作ＨＥ染色及石碳酸碱性品红法染色显示幽门螺旋菌（ＨＰ）。结果表明：４２例中晚期胃癌患者ＨＰ阳性率为２３８％，７例早期胃癌患者ＨＰ阳性率为５７１％，两者差异有高度显著性（Ｐ＜０．０１）。在ＨＰ阳性的患者，ＨＰ并不分布于癌变组织，而是分布于癌旁“正常”组织，在中晚期胃癌的ＨＰ分布较早期胃癌更稀疏。提示ＨＰ与胃癌的进展关系不大。
7 cases of early gastric cancer and 42 cases of advanced gastric cancer biopsy were stained with HE and stone carbonate basic fuchsine staining showed Helicobacter pylori (HP). The results showed that the HP positive rate of 42 patients with advanced gastric cancer was 23.8%, and the positive rate of HP in 7 patients with early gastric cancer was 57.1%. There was a significant difference between the two (P<0.01). In HP-positive patients, HP is not distributed in the cancerous tissue, but is distributed in the “normal” tissues next to the cancer. The distribution of HP in advanced gastric cancer is more sparse than that of early gastric cancer. It suggests that HP has little to do with the progression of gastric cancer.