鄱阳湖沿湖居民血吸虫病血清流行病学调查分析

• 作 者: 钟子静 曾小军 姜唯声 胡位陈 兰炜明 张智珠 高晓晖 谢峰 葛军 吕尚标
• 机 构: 广东省东莞市凤岗镇医院,江西省寄生虫病防治研究所,新建县血吸虫病防治站,
• 出 处: 实验与检验医学
• 发表日期: 2009年02期
• 关键词: 血吸虫病 血清 流行病学 分析

目的了解鄱阳湖区血吸虫病二类疫区居民抗体变化规律。方法用Kato-Katz和IHA法对居民进行病原学和血清学检查。结果该地居民血吸虫平均感染率和抗体阳性率分别为6.19%和26.67%,不同年龄组全体人群血吸虫感染率和抗体阳性率均随着年龄的增大而升高,分别在40～和50～岁组达到最高;不同年龄组全体人群感染度EPG和抗体滴度倒数的几何均数(GMRT)年龄变化规律也随着年龄的增大而升高,均在40～岁组最高,后逐渐下降。男性居民血吸虫平均感染率和抗体平均阳性率均高于女性。结论血吸虫病血清流行病学调查是判断一个地区血吸虫病流行现状的敏感指标,可作为血吸虫病流行病学监测的工具之一。

Objective To understand the changes of resident antibodies in two epidemic areas of schistosomiasis in Poyang Lake. Methods Kato-Katz and IHA methods were used for etiological and serological examination of residents. Results The average infection rate and antibody positive rate of schistosoma japonicum in this area were 6.19% and 26.67% respectively. The infection rate and antibody positive rate of schistosoma japonicum in all age groups increased with age, The age group reached the highest. The geometric mean (GMRT) of the EPG and reciprocal antibody titers in all age groups also increased with age, both of which were highest in 40 ~ . The average infection rate and average positive rate of schistosoma japonicum in male were higher than those in female. Conclusions Seroepidemiological survey of schistosomiasis is a sensitive index to judge the prevalence of schistosomiasis in a region and can be used as one of the tools for epidemiological surveillance of schistosomiasis.