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目的 对吡柔比星 ( pirarubicin ,THP)膀胱腔内灌注防治膀胱癌术后复发进行初步探讨。 方法 回顾性分析 15例膀胱癌患者的术后灌注效果。结果 THP3 0mg溶于注射用水 3 0ml行膀胱灌注 (保留 3 0分钟 ) ,可以发挥良好的抗癌疗效而无明显不良反应发生。结论 THP短期内膀胱灌注防治膀胱癌术后复发有一定的潜在应用前景 ,但其长期疗效尚待进一步观察
Objective To investigate the effect of intravesical instillation of pirarubicin (THP) on the recurrence of bladder cancer. Methods Retrospective analysis of 15 cases of bladder cancer patients after perfusion. Results THP3 0mg dissolved in water for injection 30ml bladder irrigation (retained 30 minutes), can play a good anticancer effect without significant adverse reactions. CONCLUSION: Short-term intravesical instillation of THP can prevent and treat bladder cancer recurrence after operation, which may have some potential applications. However, its long-term efficacy needs further observation