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淋巴瘤伴有单克隆免疫球蛋白(MIgs)的存在早有报道,但因文献中诊断依据及淋巴瘤分型均不统一,故对此难以评价。本文作者分析B细胞型非何杰金氏淋巴瘤(NHL)62例,按Lukes和Collins分类法分型,其中小淋巴细胞性(SLL)16例,浆细胞样淋巴细胞性(PLL)14例,滤泡中心细胞性(FCC)22例,原始免疫细胞性10例,另慢性淋巴细胞白血病(B-CLL)38例,共计100例B细胞性肿瘤。全部作血清和尿免疫电泳及血清免疫球蛋白(lgs)定量,并作冷沉淀球蛋白和冷凝集素试验。结果发现24例合并单克隆丙球蛋白病,其中B-CLL占3/38(7.9%),SLL 6/16例(39.3%),PLL 8/14例(57%),FCC 3/22例(13.6%),原
The existence of lymphoma with monoclonal immunoglobulin (MIgs) has long been reported, but it is difficult to evaluate because of the lack of uniform diagnosis and classification of lymphoma in the literature. The authors analyzed 62 B-cell non-Hodgkin’s lymphomas (NHLs) and classified them according to the Lukes and Collins classification, including 16 with small lymphocytic (SLL) and 14 with plasmacytoid lymphocytic (PLL) , 22 cases of follicular center cell (FCC), 10 cases of primitive immune cells and 38 cases of chronic lymphocytic leukemia (B-CLL), a total of 100 cases of B cell tumors. All for serum and urine immunoelectrophoresis and serum immunoglobulin (lgs) quantitative, and cryoprecipitate globulin and cold agglutinin test. Twenty-four patients with monoclonal gammopathy were found, accounting for 3/38 (7.9%) in B-CLL, 6/16 (39.3%) in SLL, 8/14 (57%) in PLL, (13.6%), the original