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目的明确人感染高致病禽流感病例的感染来源,探索是否存在人与人之间的传播,为进一步认识与防治禽流感提供科学依据。方法采用现场流行病学调查和实验室检测相结合的方法进行调查、诊断。结果发现2011年深圳首例人感染高致病性禽流感病毒(H5N1)确诊病例,无明确病、死禽接触史,密切接触者中无不明原因肺炎病例,未发现人-人传播证据。结论 2011年深圳人感染高致病性禽流感病例属感染个案,未发现人传人现象,感染来源可能与农贸市场环境有关。今后应继续加强不明原因肺炎监测,加强人感染高致病性禽流感的应急贮备、培训和健康教育。
Objective To clarify the source of infection in human cases of HPAI and to explore the existence of interpersonal transmission, so as to provide a scientific basis for further understanding and prevention of bird flu. Methods The methods of field epidemiological investigation and laboratory testing were used to investigate and diagnose. The results showed that in 2011, the first case of human confirmed HPAI in Shenzhen was confirmed. There was no clear history of contact with dead or dead birds. There were no cases of pneumonia in the close contacts and no evidence of human-human transmission was found. Conclusions In 2011, a total of cases of HPAI in Shenzhen were cases of infection, and no human-to-human transmission was found. The source of infection may be related to the market environment for farmers. In the future, pneumonia surveillance of unexplained causes should continue to be strengthened to enhance emergency response, training and health education for people infected with HPAI.