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目的:探讨影响大肠癌淋巴结转移的因素,为临床治疗提供参考。方法:对2005-2006年经手术病理确诊143例大肠癌资料进行分类整理,采用!2检验及Logistic多因素回归分析相关临床病理因素和淋巴结转移的关系。结果:大肠癌淋巴结转移与性别、年龄、肿瘤大小、肿瘤位置、肿瘤大体类型无关(P>0.05),与肿瘤侵犯肠管周径、浸润深度、组织类型、病理分级明显相关(P<0.01),以浸润深度对淋巴结转移的影响为首位。结论:影响大肠癌淋巴结转移的因素主要有侵犯肠管周径、浸润深度、组织类型、病理分级,而浸润深度为影响淋巴结转移的首要因素。
Objective: To explore the factors affecting the lymph node metastasis of colorectal cancer and provide reference for clinical treatment. Methods: The data of 143 cases of colorectal cancer confirmed by operation and pathology from 2005 to 2006 were classified and classified. The relationship between clinicopathological factors and lymph node metastasis was analyzed by Logistic regression test and Logistic regression analysis. Results: The lymph node metastasis of colorectal cancer was not related to the gender, age, tumor size, tumor location and the gross type of tumor (P> 0.05), but was significantly correlated with the tumor invasion of intestine, depth of invasion, histological type and pathological grade In order to infiltrate the depth of lymph node metastasis as the first place. CONCLUSION: The main factors influencing lymphatic metastasis of colorectal cancer are invasion of intestinal circumference, depth of invasion, histological type and pathological grade. Invasion depth is the primary factor affecting lymph node metastasis.