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目的了解广西贵港市艾滋病病毒感染者及病人的生存时间分布特征及其影响因素。方法采用回顾性研究,采用艾滋病综合防治数据信息系统中截止2013年12月31日,按所有的现住址为本地艾滋病病毒感染者及病人为研究对象,收集死亡报告病例相关信息,采用Cox比例风险回归模型分析艾滋病病毒感染者及病人生存时间的影响因素。结果死亡的2 855例艾滋病病毒感染者及病人中,2000-2007、2008、2009、2010、2011、2012、2013年分别死亡人数274人、274人、385人、407人、567人、648人、300人。平均死亡年龄为(56.71±17.10)(0.17~96岁),研究对象生存时间的中位数是9个月,接受和未接受过抗病毒治疗者的中位生存时间分别是18个月和7个月,二者差异有统计学意义(P=0.000)。多因素Cox回归分析结果显示从确证到抗病毒治疗开始时间、传播途径、是否抗病毒治疗是影响病人生存时间的密切因素。结论 2000-2013年,贵港市HIV/AIDS病人生存时间的中位数为9个月,从确证到抗病毒治疗开始时间、传播途径、是否抗病毒治疗是病人生存时间的影响因素。
Objective To understand the distribution characteristics and influencing factors of the living time of HIV-infected and patients in Guigang, Guangxi. METHODS: A retrospective study was conducted using an integrated HIV / AIDS prevention and control data system. As of December 31, 2013, all current HIV-infected patients and their patients were enrolled in this study. Relevant information on death cases were collected and Cox proportional hazards Regression model was used to analyze the influencing factors of HIV-infected patients and their survival time. As a result, among the 2 855 HIV-infected persons and their patients who died, there were 274, 274, 385, 407, 567 and 648 respectively in 2000-2007, 2008, 2009, 2010, 2011, 2012 and 2013 , 300 people. The median age of death was (56.71 ± 17.10) (0.17-96 years). The median survival time was 9 months. The median survival time was 18 months for those who received or did not receive antiviral therapy and 7 Months, the difference was statistically significant (P = 0.000). Multivariate Cox regression analysis showed that from the time of confirmation to the start of anti-virus treatment, the route of transmission, whether anti-virus treatment is a close factor affecting the patient’s survival time. Conclusions From 2000 to 2013, the median survival time of HIV / AIDS patients in Guigang was 9 months. From confirmations to the start time of anti-virus treatment, the route of transmission, whether anti-virus treatment was the influencing factor of patient survival time.