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目的 :探讨O型血孕妇IgG抗-A(B)抗原效价与新生儿血型血清学检验结果的关系。方法 :收集2015年1月至2016年1月于我院产科住院常规产检夫妻ABO血型不合的O型血孕妇160例,检测孕妇血中IgG抗-A(B)抗原的效价,对其分娩的A或B型血新生儿(113例)的脐血进行血型血清学检验,分析两者相关性。结果 :113例A或B型血新生儿中,当孕妇IgG抗-A(B)效价≥32时,新生儿红细胞被IgG抗A和抗B致敏的阳性率及血液中游离抗体的阳性率均显著增高,差异有统计学意义,P<0.05。结论:孕妇IgG抗A和抗B抗原效价的变化与新生儿血型血清学检验结果呈显著的正相关性,常规进行筛查有助于新生儿溶血的早发现、早治疗。
Objective: To investigate the relationship between the IgG anti-A (B) antigen titer of O-type pregnant women and the results of neonatal blood group serological test. Methods: From January 2015 to January 2016 in our hospital obstetrics and gynecology hospital routine abortion-incompatible ABO blood type O-type pregnant women, 160 cases of pregnant women to detect the blood IgG anti-A (B) antigen titer of their childbirth Of type A or B blood of newborns (113 cases) of cord blood serological tests, analysis of the correlation between the two. Results: In 113 newborns with type A or B blood, the positive rate of neonatal erythrocytes being sensitized by IgG anti-A and anti-B and the positive rate of free antibody in blood when the IgG anti-A (B) titer of pregnant women ≥ 32 Rates were significantly higher, the difference was statistically significant, P <0.05. Conclusion: The changes of the titer of IgG anti-A and anti-B antigen in pregnant women are positively correlated with the results of neonatal blood group serological tests. Screening routinely helps early detection and early treatment of neonatal hemolysis.