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目的:统计开封地区腹膜透析急性严重并发症的现状并对导致其发生的相关因素进行分析,从而达到早期评估、早期预警的目的。方法:回顾性分析2015-11-2016-07开封地区50例腹膜透析患者,统计腹膜透析急性严重并发症(难治性腹膜炎、高血压危象、恶性心律失常、急性心力衰竭)的发生率,将发生急性严重并发症患者根据患者透析龄分为3组:A组(透析龄<3年)、B组(3年<透析龄<6年)、C组(6年<透析龄<9年)、比较3组间差异。同时对是否发生严重并发症与可能与之相关因素(性别、年龄、家庭成员组成、收入、文化程度、居住地、T、R、BP、WBC、HB、K+、BUN、Scr、ALB、PTH、BNP)进行多因素相关性分析。结果:3组间比较,发生难治性腹膜炎、高血压危象和总发生率差异有统计学意义(P<0.05);组间两两比较:C组难治性腹膜炎、高血压危象和总发生率高于A组和B组(P<0.05);A组和B组2组间比较差异无统计学意义;人均年收入(OR=5.13)、居住地(OR=9.23)、CRP(OR=7.35)及BNP(OR=4.52)是发生急性严重并发症的独立危险因素。结论:对于农村低收入腹膜透析患者应该严格执行定期复诊及随访制度,CRP>8.2μg/ml、BNP>800ng/ml升高需要加强警惕。
OBJECTIVE: To analyze the current situation of acute serious complications of peritoneal dialysis in Kaifeng area and analyze the related factors leading to its occurrence, so as to achieve the purpose of early assessment and early warning. Methods: A retrospective analysis of 50 cases of peritoneal dialysis patients in Kaifeng from 2015-11-2016-07 was conducted. The incidence of acute and severe peritoneal dialysis complications (refractory peritonitis, hypertensive crisis, malignant arrhythmia, acute heart failure) Patients with acute serious complications were divided into 3 groups according to the dialysis age: group A (dialysis age <3 years), group B (3 years 8.2μg / ml and BNP> 800ng / ml need to be vigilant.