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目的:比较液基薄层细胞检测系统(LCT)与传统巴氏涂片法在宫颈病变筛查中的价值。方法:分别采用LCT和传统巴氏涂片两种方法进行宫颈病变筛查,并应用TBS细胞分类法进行评价。将诊断意义不明的不典型鳞状细胞(ASCUS)以上病变均列为阳性病例,并行阴道镜下组织病理学检查,将细胞学检测结果与组织学诊断结果进行对比。结果:液基薄层细胞检测法与巴氏涂片法比较,阳性率无显著性差异(P>0.05),组织病理学诊断符合率明显高于巴氏涂片组(P<0.05)。结论:LCT技术应用于宫颈细胞涂片筛查,明显提高了涂片的满意度和诊断的准确性。LCT检查异常病例配合阴道镜病理检查进行最后诊断,能及早发现宫内早期病变,是防治宫颈癌发生的关键。
Objective: To compare the value of liquid-based thin-layer cell detection system (LCT) and traditional Pap smear in cervical lesions screening. Methods: Cervical lesions were screened by LCT and traditional Pap smears, respectively, and evaluated by TBS cell sorting. The diagnosis of atypical squamous cells (ASCUS) above lesions were classified as positive cases, colposcopy under colposcopy and histopathology, the cytological test results and histological diagnostic results were compared. Results: Compared with Pap smear group, the positive rate of liquid-based thin-layer cytometry was not significantly different (P> 0.05). The coincidence rate of histopathological diagnosis was significantly higher than that of Pap smear group (P <0.05). Conclusion: The LCT technique is applied to cervical smear screening, which obviously improves the satisfaction of smear and the accuracy of diagnosis. LCT examination with abnormal colposcopy colposcopy pathological examination for the final diagnosis, early detection of early intrauterine lesions is the key to the prevention and treatment of cervical cancer.