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利用多肽合成技术在戊型肝炎病毒(HEV)的结构区内的开放读码框(ORF)-2和ORF-3区合成了P1、P2二条具有明确抗原表位的合成多肽,作为EIA法抗-HEV诊断试剂的固相抗原测定抗-HEV。在78例急性甲型肝炎中抗-HEV检出率为7.8%,慢性乙型肝
Polypeptide synthesis was used to synthesize P1 and P2 synthetic peptides with definite epitopes in the open reading frames (ORF) -2 and ORF-3 regions of the HEV structural domain as EIA method Anti-HEV Assay for Solid Phase Antigens from HEV Diagnostic Reagents. In 78 cases of acute hepatitis A anti-HEV was detected in 7.8% of chronic hepatitis B.