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近年来,通过对乙型肝炎发病机理的深入研究,人们逐渐认识倒乙型肝炎的发病和机体免疫应答及免疫调节功能紊乱密切相关,部分病人表现为超敏状态,部分病人则表现为免疫功能不足,因此人们提出了兔疫抑制与免疫促进治疗的新概念.1 免疫抑制剂肾上腺皮质激素单一或与其他免疫抑制剂合用,直至70年代还是治疗慢性乙型肝炎的常规方法,80年代初临床观察发现无论是长疗程或是短疗程,由于激素的负效应——免疫抑制,从而增加
In recent years, through the in-depth study of the pathogenesis of hepatitis B, people gradually understand the incidence of hepatitis B and the immune response and immune dysfunction is closely related to the disorder, some patients showed hypersensitivity state, while some patients showed immune function Deficiencies, so people put forward a new concept of suppression of immune suppression and immunization.1 The immunosuppressive agents corticoids alone or in combination with other immunosuppressive agents until the 1970s is the conventional treatment of chronic hepatitis B, the early 80s clinical Observed that both the long course or short course of treatment, due to the negative effect of hormones - immunosuppression, thereby increasing