In vivo Anti-tumor Effect of siRNA Against STAT3 on Transplanted Lewis Lung Cancer in Mice

• 作 者: WANG Chun-guang WANG Rong-you
• 机 构: DepartmentofThoracicSurgery,DepartmentofPathology
• 出 处: 高等学校化学研究：英文版
• 发表日期: 2008年3期
• 关键词: 肺癌 体内抗肿瘤效果 STAT3 SIRNA STAT3 Lewis lung cancer siRNA
• 基金项目: Supported by the Grants from the Science and Technology Department of Jilin Province, China（Nos.200505120 and 20050408-1）, the Burea of Science and Technology of Changchun City, China（No.2006135）, the

This study aims at determining the therapeutic effect of knockdown of signal transducers and activators of transcription3(STAT3) gene expression by short interference RNA(siRNA) on transplanted Lewis lung cancer in mice in vivo. pSilencer 2.1-U6 STAT3 siR