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目的:观察中药周期加灌肠综合防治卵巢子宫内膜异位囊肿术后复发的临床疗效。方法:将60例行腹腔镜手术的卵巢子宫内膜异位囊肿患者随机分为治疗组和对照组各30例;治疗组采用中药周期加灌肠综合治疗;对照组予西药丹那唑胶囊治疗。观察比较2组临床疗效、复发率、妊娠率及副反应发生率。结果:总有效率治疗组为66.67%,对照组为53.33%,2组比较,差异无显著性意义(P>0.05)。2组患者随访1年,复发率治疗组为16.67%,对照组为40.00%,2组比较,差异有显著性意义(P<0.05)。随访结束后,妊娠率治疗组为60.00%,对照组为33.33%,2组比较,差异有显著性意义(P<0.05)。治疗组无患者出现副反应,对照组副反应发生率为16.67%,2组比较,差异有显著性意义(P<0.05)。结论:中药周期加灌肠能有效降低卵巢子宫内膜异位囊肿术后复发,提高患者受孕率,值得临床推广应用。
Objective: To observe the clinical efficacy of traditional Chinese medicine plus enema in the prevention and treatment of ovarian endometriosis recurrence after surgery. Methods: Sixty patients undergoing laparoscopic surgery for ovarian endometriosis were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated with traditional Chinese medicine plus enema. The control group was treated with Danazol capsule. The clinical efficacy, relapse rate, pregnancy rate and incidence of side effects in the two groups were observed and compared. Results: The total effective rate was 66.67% in the treatment group and 53.33% in the control group. There was no significant difference between the two groups (P> 0.05). The two groups were followed up for 1 year, the recurrence rate was 16.67% in the treatment group and 40.00% in the control group. There was significant difference between the two groups (P <0.05). At the end of follow-up, the pregnancy rate was 60.00% in the treatment group and 33.33% in the control group. There was significant difference between the two groups (P <0.05). There were no side effects in the treatment group. The incidence of side effects in the control group was 16.67%. There was significant difference between the two groups (P <0.05). Conclusion: Chinese medicine plus enema cycle can effectively reduce ovarian endometriosis recurrence after surgery to improve the rate of conception in patients, it is worth promoting the clinical application.