论文部分内容阅读
目的:探究酮替芬应用于哮喘治疗的临床效果。方法:选取我院2012年11月~2015年11月收治的60例哮喘患者,随机分为观察组和对照组,观察组30例患者采用常规治疗联合酮替芬治疗,对照组30例患者采用常规治疗联合沙丁胺醇治疗,比较两组患者治疗效果、肺通气功能指标、血气分析指标。结果:观察组有效23例,显效5例,治疗总有效率为93.3%;对照组有效17例,显效6例,治疗总有效率为76.7%;可以明显看出观察组治疗总有效率显著高于对照组,组间比较差异明显,具有统计学意义。治疗后两组患者的肺通气功能指标均有所改善,观察组FEV1、FVC改善情况明显优于对照组。组间比较差异明显,具有统计学意义P<0.05。结论:酮替芬能有效地降低气道高反应,预防哮喘发作,改善肺通气功能,缓解临床症状,值得在临床中推广使用。
Objective: To investigate the clinical effect of ketotifen in the treatment of asthma. Methods: Sixty asthma patients admitted from November 2012 to November 2015 in our hospital were randomly divided into observation group and control group. Thirty patients in observation group were treated with conventional therapy combined with ketotifen, and 30 patients in control group Conventional treatment combined with salbutamol treatment, the treatment effect of two groups were compared, pulmonary ventilation function index, blood gas analysis index. Results: In the observation group, 23 cases were effective and 5 cases were markedly effective. The total effective rate was 93.3%. In the control group, 17 cases were effective and 6 cases markedly effective. The total effective rate was 76.7%. The total effective rate of the observation group was obviously high In the control group, the difference between the groups was significant and statistically significant. After treatment, both groups of patients with pulmonary ventilation function indicators have improved, the observation group FEV1, FVC improved significantly better than the control group. Significant difference between the groups was statistically significant P <0.05. Conclusion: Ketotifen can effectively reduce airway hyperresponsiveness, prevent asthma attacks, improve pulmonary ventilation and relieve clinical symptoms. It is worth to be used clinically.