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NT使胎鼠体重增长缓慢、胎鼠骨骼发育迟缓、肋骨畸形率增高、行为发育(?)常、雌鼠受孕率降低。800mg/kg 组妊鼠骨髓、脐带血及胎鼠肝血PCE(?)核率增高。TNT 染毒小鼠精子活动率降低、精子畸形率增高、精子数减少、睾丸细胞染色体畸变率增高,而且睾丸和卵巢形态学在电镜和光镜下均有改变。TNT 染毒大鼠血清E_2、FSH、LH 及T 含量亦有改变。结果表明(?)NT 对实验动物是具有生殖毒性的化学物质。
NT slow growth of fetal rat weight, fetal rat skeletal growth, rib deformity increased, behavioral development (?) Often, female rats decreased pregnancy rate. 800mg / kg group of pregnant mice bone marrow, umbilical cord blood and fetal liver and blood PCE (?) The nuclear rate increased. The activity of sperm decreased, the sperm deformity increased, the sperm count decreased, the chromosome aberration rate of testicular cells increased, and the morphology of testis and ovary changed under electron microscope and light microscope. The content of serum E2, FSH, LH and T in TNT-infected rats also changed. The results show that (?) NT is a reproductive toxic chemical in laboratory animals.