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目的:通过资料的分析比对研究妊娠期糖代谢发生异常与妊娠期高血压疾病(PHD)的关系。方法:对2010年至2014年在我院分娩住院的6000例孕妇的临床资料进行回顾性分析,分析内容主要是针对不同等级糖代谢有异常的孕妇在妊娠期间发生高血压疾病的情况;比较孕妇在不同的糖负荷之后糖化血红蛋白水平、血糖水平以及胰岛素抵抗指数的不同。结果:6000例孕妇并发PHD228例,发生率3.8%,妊娠期间糖代谢发生异常孕妇1248例,发生率20.8%;妊娠期糖代谢发生异常孕妇75例并发PHD,发生率6.0%;糖代谢正常的孕妇PHD发生率为3.3%,两者的差异具有统计学意义(P<0.001)。结论:妊娠期的糖代谢发生异常的孕妇更加容易发生妊娠期的高血压疾病;如果糖代谢发生异常的程度的加重,则妊娠期发生高血压疾病的几率则呈现增加的趋势。
OBJECTIVE: To investigate the relationship between abnormal glucose metabolism in pregnancy and hypertensive disorder complicating pregnancy (PHD) through data analysis and comparison. Methods: The clinical data of 6000 pregnant women who were hospitalized in our hospital from 2010 to 2014 were analyzed retrospectively. The main contents of the analysis were the incidence of hypertensive disorders during pregnancy in pregnant women with different grades of glucose metabolism. Compared with pregnant women Glycated hemoglobin levels, blood glucose levels, and insulin resistance index differ after different glucose loads. Results: There were 6000 cases of PHD in 6000 pregnant women with the incidence of 3.8%. There were 1248 pregnant women with abnormal glucose metabolism in pregnancy, the incidence rate was 20.8%. 75 pregnant women with abnormal glucose metabolism were complicated with PHD, the incidence rate was 6.0%. The normal glucose metabolism The incidence of PHD in pregnant women was 3.3%, the difference between the two was statistically significant (P <0.001). Conclusion: Pregnant women with abnormal glucose metabolism during pregnancy are more likely to develop hypertensive disorders during pregnancy. If the degree of abnormal glucose metabolism is increased, the incidence of hypertensive disorders in pregnancy tends to increase.