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最近,国外正在研究一种治疗胆石症的新药,名为鹅去氧胆酸(Chenodeoxycholicacid),给胆固醇胆石症患者服用后,能使胆石渐渐溶解,这样就不必进行外科手术。鹅去氧胆酸是一种天然的胆酸,以和甘氨酸或牛磺氨酸相结合的形式,存在于人、牛、猪及鹅、鸡等家禽胆汁中,在人胆汁中占45％,为最多的一种胆汁酸。其化学名为3α,7α-二羟基-5β-胆烷酸,为无味、无色的针状结晶(醋酸乙酯中重结晶),可溶于甲醇、乙醇、丙酮、冰醋酸,不溶于水、石油醚、苯。其结构式为
Recently, a new drug for the treatment of cholelithiasis is being studied abroad, called Chenodeoxycholic acid. After being given to patients with cholesterol cholelithiasis, gallstone can gradually dissolve so that no surgical operation is required. Chenodeoxycholic acid is a natural cholic acid, and in the form of combining with glycine or taurine, is present in the bile of humans, cattle, pigs, geese and chickens, and accounts for 45% of human bile. A bile acid for the most. Its chemical name is 3α, 7α-dihydroxy-5β-cholanoic acid, which is odorless and colorless acicular crystals (recrystallized from ethyl acetate), soluble in methanol, ethanol, acetone and glacial acetic acid, insoluble in water , Petroleum ether, benzene. Its structural formula is