3D numerical study of tumor blood perfusion and oxygen transport during vascular normalization

• 作 者: Jie WU Yan CAI Yi FU Zhujun TA
• 机 构: MinistryofEducationofChina（MOE）KeyLaboratoryofHydrodynamics,SchoolofNavalArchitecture,SchoolofBiolog
• 出 处: 应用数学和力学：英文版
• 发表日期: 2015年2期
• 关键词: 肿瘤血管生成 三维数值模拟 运输过程 血液灌流 正常化 氧气 灌注 血细胞比容 tumor hypoxia environment oxygen transpo
• 基金项目: Project supported by the National Natural Science Foundation of China（Nos.11102113 and81301816）,the New Teachers Start Program of Shanghai Jiao Tong University,the Chenxing Young Scholars Program B of

The changes of blood perfusion and oxygen transport in tumors during tumor vascular normalization are studied with 3-dimensional mathematical modeling and numerical simulation. The models of tumor angiogenesis and vascular-disrupting are used to simulate