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目的:探讨低剂量米非司酮联合妈富隆治疗功能失调性子宫出血的临床效果。方法:共收集2008年1月～2011年6月60例功能失调性子宫出血患者。采用随机数字法分为两组,A组患者给予单独低剂量米非司酮治疗;B组患者给予低剂量米非司酮联合妈富隆治疗。结果:两组患者总有效率分别为90.0%和96.7%。治疗后两组间控制出血时间及不良反应比较,与A组(单独低剂量米非司酮组)患者相比,B组(低剂量米非司酮联合妈富隆组)患者控制出血时间及不良反应明显比较低(P<0.05)。结论:对功能失调性子宫出血患者采用低剂量米非司酮联合妈富隆治疗疗效比较明显,且治疗后不良反应比较小,安全可靠,值得临床推广应用。
Objective: To investigate the clinical effect of low dose mifepristone combined with Marvelon on dysfunctional uterine bleeding. Methods: A total of 60 dysfunctional uterine bleeding patients were collected from January 2008 to June 2011. The patients were divided into two groups randomly. The patients in group A were treated with low dose mifepristone alone. The patients in group B were treated with low dose mifepristone plus marvelon. Results: The total effective rates of the two groups were 90.0% and 96.7% respectively. Bleeding time and adverse reactions were compared between the two groups after treatment, and patients in group B (low-dose mifepristone combined with marvelon) had control of bleeding time and adverse events compared with those in group A (low-dose mifepristone alone) Response was significantly lower (P <0.05). Conclusion: The treatment of dysfunctional uterine bleeding patients with low dose of mifepristone combined with Marvelon treatment is obvious, and the adverse reactions after treatment is relatively small, safe and reliable, worthy of clinical application.