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目的观察肝动脉温热化疗栓塞(TAHCE)结合CT引导下经皮肝穿瘤内注射醋酸(PAI)治疗原发性肝癌的临床疗效。方法选取我科2008年3月到2013年3月间收治的102例经病理证实为原发肝癌患者,其中男78例,女24例,年龄30~72岁,平均45岁,随机分成A、B两组。A组51例先行TAHCE治疗,术后15~20d在CT引导下行PAI治疗2~3次;B组51例仅行TAHCE治疗。结果治疗两个周期后比较AFP下降程度和肿块缩小情况均有统计学意义(P<0.01)。1a、3a、5a生存率比较,A组高于B组。结论 TAHCE结合PAI治疗原发性肝癌有很好临床疗效。
Objective To observe the curative effect of transcatheter arterial chemoembolization (TAHCE) combined with CT guided percutaneous transhepatic injection of acetic acid (PAI) in the treatment of primary liver cancer. Methods From March 2008 to March 2013, 102 cases of primary hepatocellular carcinoma confirmed by pathology were selected, including 78 males and 24 females, aged from 30 to 72 years (average 45 years old) and were randomly divided into A, B two groups. A group of 51 cases of first-line TAHCE treatment, 15 ~ 20d after CT-guided PAI treatment 2 to 3 times; B group 51 cases only TAHCE treatment. Results After two cycles of treatment, the decrease of AFP and the shrinkage of tumor were statistically significant (P <0.01). The survival rates of 1a, 3a and 5a were higher in group A than in group B. Conclusion TAHCE combined PAI treatment of primary liver cancer has a very good clinical effect.