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目的:探讨朗格罕细胞组织细胞增生症累及垂体的MR表现及相关临床表现。方法:搜集了6例确诊为朗格罕细胞组织细胞增生症并垂体表现异常的患儿,男5例,女1例,年龄2～11岁,平均(6±3)岁,对其影像及临床表现进行回顾性分析。结果:临床患儿主要以头面部包块,多饮、多尿等就诊。头颅MR平扫(T1WI)表现6例患儿神经垂体高信号全部消失,垂体柄增粗5例,垂体柄著征1例,垂体饱满1例,其中3例治疗后复查垂体及垂体柄均有变化。结论:神经垂体高信号消失,垂体柄增粗或著征为朗格罕细胞组织细胞增生症累及垂体的头颅MR表现。累及垂体者临床几乎都有多饮、多尿表现。目前,MRI是诊断朗格罕细胞组织细胞增生症累及垂体的唯一可靠的影像学检查方法,并对治疗后病情随访有重要作用。
Objective: To investigate the MR findings and related clinical manifestations of pituitary involved in Langerhans cell histiocytosis. Methods: Six children diagnosed as Langerhans cell histiocytosis with abnormal pituitary were collected. There were 5 males and 1 females, aged 2 to 11 years (mean, 6 ± 3 years) Clinical manifestations were retrospectively analyzed. Results: Clinical children with head and face mass, drink more, more urine and other treatment. 6 cases of neurohypophysis high signal disappeared, pituitary stalk thickening in 5 cases, pituitary stalk sign in 1 case, pituitary full in 1 case, of which 3 cases were reviewed after treatment of pituitary and pituitary stalk Variety. Conclusion: The high signal of the neurohypophysis disappeared and the pituitary stalk was thick or marked as a manifestation of cranial MR of the pituitary involved in Langerhans cell histiocytosis. Involved in pituitary almost have clinical drink more, more urine performance. At present, MRI is the only reliable imaging method to diagnose the pituitary involved in Langerhans cell histiocytosis, and plays an important role in the follow-up of the patients after treatment.