论文部分内容阅读
本研究应用生物学方法检测27例多发性硬化（MS）患者血清和脑脊液（CSF）白细胞介素-6（IL－6）水平，以探讨IL－6在MS发病中的作用。结果显示MS患者血清IL-6水平显著高于其他非炎症性神经病（NIND）组及正常对照（NC）组，其CSFIL－6水平亦显著高于NIND组；但MS患者血清与CSFIL-6水平不呈线性相关，血清IL-6水平随病情稳定而下降。本研究结果提示IL－6可能参与MS的免疫病理过程。
In this study, serum and CSF levels of interleukin-6 (IL-6) in 27 patients with multiple sclerosis (MS) were detected by using biological methods to explore the role of IL-6 in the pathogenesis of MS. The results showed that the level of serum IL-6 in MS patients was significantly higher than that in other noninflammatory neuropathy (NIND) and normal control (NC) groups, and the level of CSFIL-6 in MS patients was significantly higher than that in NIND group Not linearly correlated, serum IL-6 levels decreased with stable disease. The results suggest that IL-6 may be involved in the immunopathological process of MS.