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[目的]观察软坚散结散联合甲状腺素片治疗甲状腺腺瘤疗效。[方法]使用随机平行对照方法,将70例门诊患者按掷骰子法随机分为两组。对照组35例左旋甲状腺素片,100ug/次,2次/d。治疗组35例软坚散(醋柴胡6g,牡蛎30g,猫爪草、玄参、红花、川芎各10g,橘红15g,醋香附10g,白芍30g,醋郁金10g,黄芩12g,当归10g,昆布、海藻各12g,丹参30g,夏枯草15g,土贝母10g,山慈菇12g,全蝎9g),1剂/d,水煎200mL,早晚口服;左旋甲状腺素片治疗同对照组。连续治疗14d为1疗程。观测临床症状、甲状腺腺瘤性状、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈16例,显效11例,有效6例,无效2例,总有效率94.29%。对照组痊愈13例,显效8例,有效5例,无效9例,总有效率74.28%。治疗组疗效优于对照组(P<0.05)。[结论]软坚散结散联合甲状腺素片治疗甲状腺腺瘤效果显著,值得推广。
[Objective] To observe the therapeutic effect of Ruanjian Sanjie Powder combined with thyroid hormone tablets in the treatment of thyroid adenoma. [Methods] Using randomized parallel control method, 70 outpatients were randomly divided into two groups according to the method of dice. The control group of 35 cases of levothyroxine tablets, 100ug / times, 2 times / d. The treatment group 35 cases of Ruanjian San (vinegar Bupleurum 6g, oyster 30g, cat’s claw grass, Scrophulariaceae, safflower, Chuanxiong each 10g, orange 15g, vinegar with 10g, white peony root 30g, vinegar turmeric 10g, baicalin 12g, Angelica 10g, kelp, seaweed each 12g, Salvia 30g, Prunella 15g, Fritillaria 10g, Agaricus 12g, Scorpio 9g), 1 / d, decoction 200mL, sooner or later orally; levothyroxine treatment with the control group . Continuous treatment 14d for a course of treatment. Observation of clinical symptoms, thyroid adenoma traits, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Result] The treatment group cured 16 cases, markedly effective in 11 cases, effective in 6 cases, ineffective in 2 cases, the total effective rate was 94.29%. The control group cured 13 cases, markedly effective in 8 cases, effective in 5 cases, ineffective in 9 cases, the total effective rate was 74.28%. The treatment group was better than the control group (P <0.05). [Conclusion] The treatment of thyroid adenoma with Ruanjian Sanjie Powder and thyroxine tablets is effective and worthy of promotion.