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光动力学疗法(PDT)是近年来发展的一种抗癌新疗法。由于皮肤光敏副反应是PDT临床应用中的主要副作用,故寻找具有缓解或对抗光敏副反应的防治药物具有一定实用意义。本实验观察了β-胡萝卜素对小鼠皮肤光敏副反应的防治作用及其与皮肤中前列腺素E_1的关系。 实验采用18～22g昆明种小鼠,分为三组。判断PDT副反应的指标采用耳指数、皮指数和伊文思蓝染
Photodynamic therapy (PDT) is a new anticancer therapy developed in recent years. As the skin photosensitive side effects are the main side effects in the clinical application of PDT, it is of practical significance to find a preventive and therapeutic drug that has the effects of alleviating or antagonizing the photosensitive side effects. This experiment observed the β-carotene on the skin photosensitivity of the prevention and treatment of mice and its relationship with the skin prostaglandin E_1. The experiment used 18 ~ 22g Kunming mice, divided into three groups. Indicators of PDT to determine the use of ear index, skin index and Evans blue dye