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采用叶下珠复方(苦味叶下珠、三七等)联合干扰素治疗慢性乙型肝炎40例,并与干扰素治疗30例对比观察,结果显示叶下珠复方联合干扰素组治疗3个月后,临床症状改善明显,治疗总有效率为92.5％。疗效优于对照组(P<0.05)。叶下珠复方联合干扰素治疗组用HBeAg、HBV-DNA阴转率为53.0％、58.8％,与对照组比较,差异无显著性意义(P>0.05)。研究表明,叶下珠复方与干扰素联合治疗慢性乙型肝炎,在改善临床症状及改善肝功能方面具有一定的协同作用。
Forty patients with chronic hepatitis B were treated with Phyllanthus Compound (Bitter Leaf Phyllanthus, Panax Notoginseng, etc.) in combination with interferon and compared with 30 patients treated with interferon. The results showed that Phyllanthus Compound combined with interferon treatment for 3 months After clinical symptoms improved significantly, the total effective rate was 92.5%. The curative effect is better than the control group (P <0.05). Phyllis beads combined with interferon treatment group with HBeAg, HBV-DNA negative conversion rates were 53.0%, 58.8%, compared with the control group, no significant difference (P> 0.05). Studies have shown that Phyllanthus Compound and interferon combined treatment of chronic hepatitis B, in improving clinical symptoms and improve liver function has some synergy.