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目的研究甘精胰岛素联合阿卡波糖治疗2型糖尿病的临床疗效。方法 70例2型糖尿病患者,均采用甘精胰岛素联合阿卡波糖治疗,比较患者治疗前后的低血糖发生情况、血糖达标时间。结果患者经治疗后,糖化血红蛋白、空腹血糖、餐后2 h血糖各项指标均优于治疗前,对比差异有统计学意义(P<0.05)。患者经治疗后,显效63例,有效6例,无效1例,总有效率为98.6%。所有患者中,有2例患者用药后出现低血糖,比例为2.9%。结论甘精胰岛素联合阿卡波糖治疗2型糖尿病具有较好的临床疗效,可降低患者血糖,提升患者生活质量,改善其病情,值得临床推广。
Objective To study the clinical efficacy of glargine combined with acarbose in the treatment of type 2 diabetes mellitus. Methods Seventy patients with type 2 diabetes mellitus were treated with insulin glargine combined with acarbose. The incidence of hypoglycemia before and after treatment was compared with the time of reaching the blood glucose level. Results After treatment, the indexes of HbA1c, fasting blood glucose and 2 h postprandial blood glucose were all better than those before treatment, the difference was statistically significant (P <0.05). After treatment, 63 cases were markedly effective, 6 cases were effective, 1 case was ineffective, and the total effective rate was 98.6%. In all patients, 2 patients developed hypoglycaemia after medication, at a rate of 2.9%. Conclusion Glargine and acarbose in the treatment of type 2 diabetes mellitus have good clinical curative effect, which can reduce the blood sugar, improve the quality of life of patients and improve their condition, which is worthy of clinical promotion.