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十二指肠溃疡(Du)是一种多因素引起的机体紊乱性疾病,至今病因不明。五十多年来,一直认为此病与感染有关,但很少见有HSV及CMV与其有关的报道。本文作者通过检测CMV和HSV抗体来研究CMV和HSV在Du病人和健康对照人群中的发病率。作者选择150例年龄在20~66岁(平均38.6±8.8)并经内窥镜确诊的Du病人及年龄性别相当、没有症状或溃疡病家族史的健康人作对照。根据血清中胃蛋白酶原水平将Du病人分为两组;高胃蛋白酶原型(原发
Du duodenal ulcer (Du) is a multifactorial disorder caused by the body, so far the cause is unknown. For more than 50 years, the disease has always been thought to be related to infection, but there are few reports of HSV and CMV related to it. The authors investigated the incidence of CMV and HSV in Du patients and healthy controls by testing for CMV and HSV antibodies. The authors selected 150 patients aged 20-66 years (mean 38.6 ± 8.8) who were diagnosed by Endoscopy and healthy subjects with similar family history and age without symptoms or ulcer disease as controls. Du patients were divided into two groups according to serum pepsinogen level; high pepsin prototype (primary