Luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline indole complexes as biological probes

来源 :Science China(Chemistry) | 被引量 : 0次 | 上传用户:lucasyvette
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Four luminescent cyclometalated iridium(Ⅲ) dipyridoquinoxaline complexes appended with an indole moiety [Ir(N^C)2(N^N)] (PF6) (HN^C = 2-phenylpyridine, Hppy; N^N = 2-(N-(2-(indole-3-acetamido)ethyl)aminocarbonyl)dipyrido[3,2-f:2′,3′-h]quinox- aline, dpqC2indole (1a), N^N = 2-(N-(6-(indole-3-acetamido)hexyl)aminocarbonyl)dipyrido[3,2-f:2′,3′-h]quinoxaline, dpqC6indole (1b); HN^C = 7,8-benzoquinoline, Hbzq, N^N = dpqC2indole (2a), N^N = dpqC6indole (2b)) have been synthesized and characterized. Upon irradiation, all the complexes displayed moderately intense and long-lived luminescence under ambient condi-tions and in 77 K glass. On the basis of the photophysical data, the emission of the complexes has been assigned to an excited state of triplet metal-to-ligand charge-transfer (3MLCT) ((dπ(Ir)→π*(N^N)) character. Cyclic voltammetric studies revealed indole-based and iridium-based oxidations at ca. +1.10 V and +1.24 V vs. SCE, respectively, and ligand-based reductions at ca. -1.07 to-2.29 V vs. SCE. The interactions of the complexes with an indole-binding protein, bovine serum albumin (BSA), have been examined by emission titrations. Four luminescent cyclometalated iridium (Ⅲ) dipyridoquinoxaline complexes appended with an indole moiety [Ir (N ^ C) 2 (N ^ N)] (PF6) - (2- (indole-3-acetamido) ethyl) aminocarbonyl) dipyrido [3,2- f: 2 ’, 3’-h] quinoxaline, dpqC2 indole Hn ^ C = 7,8-benzoquinoline, Hbzq, N ^ (6-indole-3-acetamido) hexyl) dipyrido [3,2- f: 2 ’, 3’-h] quinoxaline, dpqC6indole N = dpqC2indole (2a), N ^ N = dpqC6indole (2b)) have been synthesized and characterized. Upon irradiation, all the complexes showed moderately intense intense and long- lived luminescence under ambient conditions and in 77 K glass. On the basis of the photophysical data, the emission of the complexes has been assigned to an excited state of triplet metal-to-ligand charge-transfer (3MLCT) (dπ (Ir) → π * (N ^ N)) character. Cyclic voltammetric studies revealed indole-based and iridium-based oxidations at ca. +1.10 V and +1.24 V vs. SCE, respectively, and ligand-based reductions at ca . -1.07 to-2.29 V vs. SCE. The interactions of the complexes with an indole-binding protein, bovine serum albumin (BSA), have been examined by emission titrations.
其他文献
“十五”期间,我们紧紧围绕中油集团公司安全培训工作要求,结合公司实际,明确责任、完善措施,规范管理、强化落实,积极组织开展了员工安全培训工作,有效地提高了员工安全生产
本文主要是介绍了几种高速公路放线测量的方法以及这些方法的特点、工作过程和注意事项。 This article is mainly introduced several methods of highway line measuremen
始料未及啊!吴成群走了,连声招呼都来不及打就带着天大的遗憾匆匆上路了。就在临走前的三四天,电话里他还雄心勃勃、信心满满地对我说,他要在2015年之前创作百幅作品,办一次
展位面积达1300多平方米的丹东黄海,在第六届北京国际商用车展上带来了8款精品车型及一款复合式全承载车身骨架总成。黄海,这个一向以半承载公交车为主打产品的客车制造企业,
对于这部制作费用高达1.8亿的《环太平洋》,导演吉尔莫·德尔·托罗到底有多爱?从他拒绝筹拍了5年的《霍比特人》就可见一斑。为了这部电影,他算得上煞费苦心。影片其窦
我总感到,从事书法艺术者,除理性的思考作为内在流程和底蕴使书法家的艺术更为深刻外,浓郁的感情、彭湃的激情,对艺术近于刻骨铭心的痴情则是造就书法家更为重 I always fee
对于现阶段公路桥梁软土地基施工过程中的主要问题进行全面分析,能够帮助我们进一步明晰公路桥梁软土地基施工工作中的重点环节与核心要求,从而为公路桥梁建设施工的有序开展
目的:评价89Sr治疗前列腺癌骨转移的临床疗效。方法:对确认前列腺癌骨转移伴骨痛的116例患者,行双侧睾丸切除术+内分泌药物+89Sr治疗。89Sr治疗静脉给药,剂量1.48~2.22MBq(40~6
四年一度的世界杯在六月中打响。三十二支飞扬劲旅,六十四场精彩比赛所组成的足球饕餮大餐,想必已经让很多双栖球迷、车迷热血沸腾。其实,同样是讲究速度、技巧、激情……足
本文从水泥混凝土路面再生技术、现场冷再生技术、沥青再生技术三个方面对于路面再生技术在公路重建工程中的应用进行了探讨,以供参考。 This paper discusses the applicat