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高血压是一种多因素疾病,是心血管病的一个重要的独立危险因素。运动训练是治疗高血压最重要的非药物治疗策略之一,然而,运动使心脏发生线粒体适应改变的机制仍然不清楚。该文旨在探讨中等强度运动训练对高血压动物模型病理发展前后线粒体蛋白质组的影响。方法:20只基因型相同的雄性自发性高血压大鼠(spontaneous hypertensive rats,SHR)分为6
Hypertension is a multifactorial disease and is an important independent risk factor for cardiovascular disease. Exercise training is one of the most important non-drug treatment strategies for the treatment of hypertension. However, the mechanism by which exercise changes mitochondria in the heart remains unclear. This paper aims to investigate the effect of moderate-intensity exercise training on the mitochondrial proteome in hypertensive animal models before and after the pathological development. Methods: Twenty male spontaneously hypertensive rats (SHR) of the same genotype were divided into 6