论文部分内容阅读
目的研究纳米碳混悬液在贲门癌手术中的实际淋巴示踪效果。方法 60例贲门癌患者随机分为实验组和对照组,各30例,实验组患者手术中先向肿瘤周围注入纳米碳混悬液后再行根治术,对照组患者直接行贲门癌根治术,不应用纳米碳混悬液。记录分析两组淋巴结数量、黑染淋巴结数量及淋巴结转移情况。结果 1实验组平均每例清除13.7个淋巴结,淋巴结黑染率为60.3%。对照组平均每例清除11.5个淋巴结。实验组淋巴结检出数明显高于对照组(P<0.05)。2实验组组黑染淋巴结转移率37.5%,对照组淋巴结转移率24.3%,实验组黑染淋巴结转移率高于对照组(P<0.05)。3手术时间、出血量、及术后并发症发生率两组均无明显差异。结论纳米碳混悬液淋巴示踪效果满意,操作简便,增加了手术中淋巴结清扫数目,提高手术疗效,且安全无毒。
Objective To study the actual lymphoid tracing effect of nanocarbon suspension in cardia cancer surgery. Methods Sixty patients with cardia cancer were randomly divided into experimental group and control group, with 30 cases in each. In the experimental group, the patients were treated with nano-carbon suspension around the tumor before operation and in the control group, Do not use nano-carbon suspension. Record and analyze the number of lymph nodes, the number of black-stained lymph nodes and lymph node metastasis. Results 1 An average of 13.7 lymph nodes were removed in each experimental group, with black stained rate of 60.3%. The control group, on average, cleared 11.5 lymph nodes. The number of lymph nodes in experimental group was significantly higher than that in control group (P <0.05). The rate of lymph node metastasis was 37.5% in experimental group and 24.3% in control group. The rate of metastasis in experimental group was higher than that in control group (P <0.05). There was no significant difference between the two groups in the operation time, the amount of bleeding, and the incidence of postoperative complications. CONCLUSIONS: The effect of nano-carbon suspension in lymphatic tracing is satisfactory, the operation is simple, the number of lymphadenectasia during operation is increased, the curative effect is improved, and the drug is safe and nontoxic.