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介绍过期专利抗癌药物比卡鲁胺的基本性能和作用。并概述了分别以溴丙酮、2-甲基丙烯酰氯、2-甲基丙烯酸甲酯、2,3-二羟基-2-甲基丙酸以及丙酮酸或丙酮酸酯为起始原料合成比卡鲁胺的方法。其中以丙酮酸或丙酮酸酯为原料的合成方法为最佳。
Describes the basic properties and effects of expired patent anticancer drug bicalutamide. In addition, the synthesis of ratio cards with bromoacetone, 2-methacryloyl chloride, 2-methyl methacrylate, 2,3-dihydroxy-2-methylpropionic acid and pyruvic acid or pyruvate Lu amine method. Which pyruvate or pyruvate as raw materials for the synthesis of the best.