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目的 :研究麝香保心丸对心肌梗死的影响。方法 :使用家兔心肌梗死模型 ,比较服用麝香保心丸或美托洛尔对家兔心肌的梗死范围、心电图指标和血浆肌酸磷酸激酶的影响。结果 :与阴性对照组比较 ,服用麝香保心丸或美托洛尔的家兔 ,其结扎后梗死范围均明显减少 (P <0 .0 1)。麝香保心丸组和美托洛尔组心电图的ST的升高幅度也均显著低于对照组 (P <0 .0 5)。同样 ,麝香保心丸组和美托洛尔组CPK的上升幅度均显著小于对照组 (P <0 .0 1)。结论 :麝香保心丸能改善心肌缺血引起的心肌梗死
Objective: To study the effect of Shexiang Baoxin Pill on myocardial infarction. Methods: Rabbit model of myocardial infarction was used to compare the myocardial infarction range, ECG indexes and plasma creatine phosphokinase of the musk heart pill or metoprolol. Results: Compared with the negative control group, the rabbits taking Shexiang Baoxin Pill or metoprolol had significantly reduced infarct size after ligation (P <0.01). The increase of ST in the musk pill group and metoprolol group was also significantly lower than that in the control group (P <0.05). Similarly, the increase in CPK in the musk pill and metoprolol group was significantly less than that in the control group (P <0.01). Conclusion: Shexiang Baoxin Pill can ameliorate myocardial infarction caused by myocardial ischemia