miR-200c Inhibits Metastasis of Breast Cancer Cells by Targeting HMGB1

• 作 者: 常保萍 王东生 邢建武 杨少华 褚倩 于世英
• 机 构: DepartmentofOncologTongjiHospital,DepartmentofOncology,KingMedDiagnostics
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2014年2期
• 关键词: 乳腺癌细胞 WESTERN印迹法 HMGB1 转染细胞 RT-PCR 迁移能力 目标预测 生物信息学 breast cancer miR-200c HMGB
• 基金项目: The project was supported by the Innovation Foundation of Excellent Intellectuals in Henan Province （No. 2109901）.

miR-200c has been shown to regulate the epithelial-mesenchymal transition(EMT) by inhibiting ZEB1 and ZEB2 expression in breast cancer cells. This study further examined the role of miR-200c in the invasion and metastasis of breast cancer that goes beyond