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为了达到低费用和短疗程治疗伤寒的目的,本文作者在儿童和成人中进一步评估了头孢三嗪5日疗程治疗伤寒的效果。 本研究是在孟加拉国国际腹泻病研究中心进行。病人的年龄为6月龄～60岁;发热4天以上;腹泻的定义为24小时内3次以上的水样便;伤寒沙门氏菌肥达氏试验检测O凝集索滴度>1:80。对有上述临床表现的患者作血和/或粪便培养,伤寒沙门氏菌阳性者可确诊。有黄疸、胃肠出血或穿孔、近期有抗生素治疗史和已知有青霉素或头孢菌素类过敏史者除外,要求患者住院治疗14天。
In order to achieve low cost and a short course of treatment for typhoid fever, the authors further evaluated the effect of 5-day treatment of typhoid on ceftriaxone in children and adults. This study was conducted at the International Center for Diarrheal Disease Research in Bangladesh. Patients aged 6 months to 60 years; fever more than 4 days; diarrhea is defined as more than three times within 24 hours of watery stool; Salmonella typhoid Festa test O coalescent titers> 1:80. For patients with the above clinical manifestations of blood and / or stool culture, Salmonella typhi can be diagnosed. Have jaundice, gastrointestinal bleeding or perforation, the recent history of antibiotic treatment and history of known penicillin or cephalosporins allergy, except requiring hospitalization for 14 days.