论文部分内容阅读
目的了解门诊慢性乙型肝炎和慢性丙型肝炎患者的生存质量及其影响因素。方法选取2012年3月-2014年3月在北京大学第三医院门诊就诊的慢性乙型肝炎和慢性丙型肝炎患者为肝炎组,选择同期无明显躯体及精神症状随同患者就诊的家属和进行体检的健康志愿者为对照组,采用SF-36、CLDQ和SSRS量表对肝炎组和对照组进行问卷调查。计量资料组间比较采用成组t检验,计数资料组间比较采用χ2检验,采用多元线性回归分析探讨影响生存质量的相关因素。结果 SF-36量表中肝炎组的生理职能、一般健康状况、精力、社会功能、情感职能、精神健康均低于对照组(P值均<0.05);CLDQ量表中肝炎组的系统症状、情感、焦虑均低于对照组(P值均<0.05)。SSRS调查发现肝炎组的客观支持、主观支持、对支持的利用度及总分均低于对照组(P值均<0.05)。多元线性回归分析得出影响肝炎患者生存质量的主要因素有年龄、性别、职业、婚姻状况、经济收入、社会支持中的主观支持和对支持的利用度等。结论门诊慢性乙型肝炎和慢性丙型肝炎患者的生存质量明显下降。年龄大、女性、离异、农民、经济收入低、主观支持少和对支持的利用度低的患者更需要关注其生存质量,医务人员应该给予患者个体化的健康指导。
Objective To understand the quality of life and its influencing factors in outpatients with chronic hepatitis B and chronic hepatitis C. Methods From March 2012 to March 2014, patients with chronic hepatitis B and chronic hepatitis C were enrolled in the Third Hospital of Peking University. Patients who had no significant physical and mental symptoms during the same period were enrolled in the study. Healthy volunteers as the control group, using the SF-36, CLDQ and SSRS scale hepatitis group and control group were investigated. Data between groups were compared using group t-test, count data between groups using χ2 test, multivariate linear regression analysis to explore the impact of quality of life related factors. Results The physical function, general health, energy, social function, emotional function and mental health in the hepatitis group were significantly lower than those in the control group on the SF-36 scale (all P <0.05). In the CLDQ scale, Emotion and anxiety were lower than the control group (P <0.05). SSRS survey found that objective support, subjective support, supportive utilization and total score of hepatitis group were lower than those of the control group (all P <0.05). Multivariate linear regression analysis showed that the main factors affecting the quality of life of hepatitis patients are age, gender, occupation, marital status, economic income, subjective support in social support and utilization of support. Conclusion The quality of life of outpatients with chronic hepatitis B and chronic hepatitis C is obviously decreased. Patients with older age, women, divorced farmers, low economic income, low subjective support and low utilization of support should pay more attention to the quality of their life, and medical personnel should give patients individualized health guidance.