Kaposi’s肉瘤的放射治疗

来源 :中华放射肿瘤学杂志 | 被引量 : 0次 | 上传用户:Empty0
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目的:探讨Kaposi肉瘤的发展现律,临床特点及疗效。材料与方法:1985-1992年间新疆医学院肿瘤医院收治7例。维吾尔族6例,哈萨克族1例。除1例病变起始左股部有腹股沟淋巴结受累外,余6例无淋巴结及内脏受侵。用x线或60Co治疗,射野超过病灶边缘2cm-3cm,每日1.8-2.0Gy,每周5次,总剂量23-57GY。结果:首发于上肢4例,2~6年后向对侧上肢及双下肢远端扩散,进展相对较快。首发于下肢3例,内有2例经8-11年时沿同侧肢体远端扩散,1例侵及上肢,病程较慢。尽管起病部位不同,是终仍为向心性发展,生存2年以上7/7例,4年以上5/5例,5年以上4/4例。结论:本病病程较长,疗效判断也相应长;对放射线治疗有效,减症剂量10-29Gy,病变消失量28-57Gy。 Objective: To investigate the development law, clinical features and curative effect of Kaposi’s sarcoma. Materials and Methods: Seven cases were treated at the Cancer Hospital of Xinjiang Medical University from 1985 to 1992. There are 6 Uighurs and 1 Kazak. Except for 1 case of inguinal lymph node involvement in the left thigh, the remaining 6 cases were invaded without lymph nodes and viscera. With x-ray or 60Co treatment, the radiosity exceeds the edge of the lesion 2cm-3cm, 1.8-2.0Gy per day, 5 times a week, the total dose of 23-57GY. Results: The first case was in the upper extremity in 4 cases. After 2 to 6 years, the distal extremities and distal extremities of the lower extremities spread more rapidly. The first case occurred in the lower extremities in 3 cases. There were 2 cases that spread along the distal end of the same limb during 8-11 years, and 1 case invaded the upper extremity. The course was slower. Although the site of onset is different, it is still concentric development, surviving more than 2 years in 7/7 cases, more than 4 years in 5/5 cases, and more than 5 years in 4/4 cases. Conclusion: The course of the disease is longer and the efficacy is judged accordingly. It is effective for radiation therapy. The dose of the disease is 10-29 Gy, and the lesion disappears 28-57 Gy.
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