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乙型肝炎病毒(HBV)是一种嗜肝DNA病毒,感染肝细胞后松弛型部分双链环状基因组DNA进入细胞核内变成共价闭环DNA(cccDNA),并以后者的负链为模板转录为mRNA,再以此mRNA为模板逆转录为DNA。这种独特的细胞内复制方式决
Hepatitis B virus (HBV) is a hepadnavirus which, after infection of hepatocytes, partially loosens part of the double-stranded circular genomic DNA into the nucleus to become covalent closed-loop DNA (cccDNA) and transcribes the latter as a template As mRNA, and then use this mRNA as a template reverse transcription of DNA. This unique way of intracellular replication decisions